https://www.theprattlab.com/home daily 1.0 2025-02-04 https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546552546260-P1PC3A17TMB2QKSXVLSK/Untitled.jpg Home https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546553079311-4BB96G89TXDDRIW78D0U/Matt.jpg Home https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546552546260-P1PC3A17TMB2QKSXVLSK/Untitled.jpg Home https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546553079311-4BB96G89TXDDRIW78D0U/Matt.jpg Home https://www.theprattlab.com/home-1 daily 0.75 2024-12-05 https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546553801817-7EXDZ32QT1C7C6BXAX1T/Untitled.jpg Research https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1ff6b70e-5df9-47fe-a637-7125b03cad2f/Squarespace+Website-1.png Research Figure 1. O-GlcNAc and our chemical strategies to study glycosylation. (a) O-GlcNAc is a dynamic posttranslational modification of serine and threonine residues of many intracellular proteins. (b) Living cells can metabolize chemical reporters and inhibitors to enable the visualization, identification, and manipulation of protein glycosylation. https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/d12002d3-f9cb-4d1b-a1de-e656de82b7e9/Squarespace+Website-2.png Research Figure 2. Synthesis of and characterization of glycosylated proteins. We have used expressed protein ligation (EPL) to generate several O-GlcNAc modified proteins and have discovered important effects of this modification on protein aggregation, kinase signaling, and the DNA damage response. https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546553801817-7EXDZ32QT1C7C6BXAX1T/Untitled.jpg Research https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1ff6b70e-5df9-47fe-a637-7125b03cad2f/Squarespace+Website-1.png Research Figure 1. O-GlcNAc and our chemical strategies to study glycosylation. (a) O-GlcNAc is a dynamic posttranslational modification of serine and threonine residues of many intracellular proteins. (b) Living cells can metabolize chemical reporters and inhibitors to enable the visualization, identification, and manipulation of protein glycosylation. https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/d12002d3-f9cb-4d1b-a1de-e656de82b7e9/Squarespace+Website-2.png Research Figure 2. Synthesis of and characterization of glycosylated proteins. We have used expressed protein ligation (EPL) to generate several O-GlcNAc modified proteins and have discovered important effects of this modification on protein aggregation, kinase signaling, and the DNA damage response. https://www.theprattlab.com/publications daily 0.75 2026-04-01 https://www.theprattlab.com/people daily 0.75 2026-01-22 https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1622073090406-5BVS1D5EAKPB5XPOIB8X/MRP.jpg People https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/a0e26e89-d1c0-44c1-a080-896f642fcc4a/Gil4.jpg People - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/477333d1-cca8-42fc-bbf0-ff7305ec80e9/Ramon.jpg People - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/22212a23-b99a-47a2-9b10-cdb2ac198c86/Geoff.jpg People - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/2b85a168-ac61-47ee-9fdf-b74136cec21e/Rhianna.jpg People - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/95e8a0a9-40c5-4daf-8999-02ad0a0b508c/Shelley.jpg People - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546560860537-9Y8JQE2O3K3P7JH8UMR5/shape_pic-13.jpg People https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/7e961d38-1951-4fd9-84d1-e811004f3c9d/USC+People.jpg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1622073090406-5BVS1D5EAKPB5XPOIB8X/MRP.jpg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/d23cd623-5e43-4c7d-846f-452516b66172/Lester.jpg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/a0e26e89-d1c0-44c1-a080-896f642fcc4a/Gil4.jpg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/477333d1-cca8-42fc-bbf0-ff7305ec80e9/Ramon.jpg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/22212a23-b99a-47a2-9b10-cdb2ac198c86/Geoff.jpg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/2b85a168-ac61-47ee-9fdf-b74136cec21e/Rhianna.jpg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/95e8a0a9-40c5-4daf-8999-02ad0a0b508c/Shelley.jpg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/adac942d-d39a-4256-aa8a-ead411ad0c13/Jack.jpg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/4fd21343-19c3-4186-8f38-e4740af90502/Parth.jpeg https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/37684006-41ac-483d-8fd0-d2dc3f9b38c5/Hanny.JPG https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546560860537-9Y8JQE2O3K3P7JH8UMR5/shape_pic-13.jpg https://www.theprattlab.com/meetings daily 0.75 2025-08-20 https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546621895904-ZRGPTTGNT30LLPAK6PZM/USC+Meetings.jpg Meetings https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1546621895904-ZRGPTTGNT30LLPAK6PZM/USC+Meetings.jpg Meetings https://www.theprattlab.com/matts-biography daily 0.75 2026-04-01 https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1622078525410-QHYND3N0U50NEXV79IBI/MRP.jpg Matt's Biography https://images.squarespace-cdn.com/content/v1/5c2e7bd5a9e028ddcab5e400/1622078525410-QHYND3N0U50NEXV79IBI/MRP.jpg Matt's Biography